ABclonal Technology Glutamine Synthetase GLUL

Supplier:  ABclonal Technology A21856100UL

The protein encoded by this gene belongs to the glutamine synthetase family It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction This protein plays a role in ammonia and glutamate detoxification acid-base homeostasis cell signaling and cell proliferation Glutamine is an abundant amino acid and is important to the biosynthesis of several amino acids pyrimidines and purines Mutations in this gene are associated with congenital glutamine deficiency and overexpression of this gene was observed in some primary liver cancer samples There are six pseudogenes of this gene found on chromosomes 2 5 9 11 and 12 Alternative splicing results in multiple transcript variants

Catalog No. 50-000-05744