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Medchemexpress LLC Glutarimide-isoindolinone-NH-PEG4-COOH | 2927334-86-7 | 99.5% | 507.5 g·mol⁻¹ | C24H33N3O9 | 5 MG
Supplier: Medchemexpress LLC HY1387905MG
Glutarimide-Isoindolinone-NH-PEG4-COOH is a synthesized E3 ligase ligand-linker conjugate that combines a cereblon-binding glutarimide-isoindolinone core with a PEG4 linker terminating in a carboxylic acid, intended for use in PROTAC research to recruit CRBN and promote ubiquitin-proteasome-mediated degradation of target proteins.
- Designed for PROTAC development to recruit cereblon E3 ligase.
- PEG4 linker with terminal carboxylic acid enables facile conjugation to target ligands.
- High reported purity suitable for research applications.
- Soluble in DMSO; published in vitro and in vivo formulation guidance available.
- Store at -20°C and protect from light; stability guidance provided for solutions.
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