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Medchemexpress LLC Glyburide-d11 | 1189985-02-1 | C23H17D11ClN3O5S | 1 MG
Supplier: Medchemexpress LLC HY15206S1MG
Glyburide-d11 is the deuterium labeled Glibenclamide, an orally active ATP-sensitive K+ channel (KATP) inhibitor. It is used for research related to diabetes and obesity. Glyburide-d11 inhibits P-glycoprotein, directly binds and blocks the SUR1 subunits of KATP, and inhibits the cystic fibrosis transmembrane conductance regulator protein (CFTR). It interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability and can induce autophagy.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Inhibits P-glycoprotein
- Blocks SUR1 subunits of KATP
- Inhibits cystic fibrosis transmembrane conductance regulator protein (CFTR)
- Interferes with mitochondrial bioenergetics
- Can induce autophagy
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