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Medchemexpress LLC Glyburide-d3 | 1219803-02-7 | C23H25D3ClN3O5S | 5 MG
Supplier: Medchemexpress LLC HY15206S15MG
Glyburide-d3 is the deuterium labeled Glibenclamide. Glibenclamide (Glyburide) is an orally active ATP-sensitive K+ channel (KATP) inhibitor used for diabetes and obesity research. It inhibits P-glycoprotein, directly binds and blocks the SUR1 subunits of KATP, and inhibits the cystic fibrosis transmembrane conductance regulator protein (CFTR). It interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability and can induce autophagy.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Inhibits P-glycoprotein.
- Blocks SUR1 subunits of KATP.
- Inhibits the cystic fibrosis transmembrane conductance regulator protein (CFTR).
- Interferes with mitochondrial bioenergetics.
- Induces autophagy.
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