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AdipoGen Glyburide USP
Supplier: AdipoGen AGCR13613G010
Chemical. CAS 10238-21-8. Formula C23H28ClN3O5S. MW 494. Antidiabetic compound. Binds to and activates the ATP-sensitive potassium channels KATP inhibitory regulatory subunit sulfonylurea receptor 1 SUR1. Causes cell membrane depolarization and opening of voltage-dependent calcium channel. Increases intracellular calcium and stimulates insulin secretion in beta cells NLRP3 inflammasome inhibitor. Broad-spectrum ATP-binding cassette ABC transporter inhibitor. Shown to have anti-leishmanial activity. Potential inhibitor of collagenases.
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