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Sigma Aldrich Glycerol formal

Catalog No. 49920500ML Shop All MilliporeSigma Sigma Organic Chemistry Products
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MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

  • Glycerol formal (gf) is a light glycerol acetal that is composed of ~60% 5-hydroxy-1,3-dioxane and ~40% 4-hydroxymethyl-1,3-dioxolane
  • It can be prepared by reacting glycerol and formaldehyde in the presence of acid catalyst
  • The potential of gf as an injection solvent for use in toxicity testing has been reported.glycerol formal may be used in the multi-step synthesis of 9-[(2-hydroxy-1-(hydroxymethyl)ethoxy)methyl]guanine (2α-nor-2α-deoxyguanosine), an analog of acyclovir
  • It may be used in the preparation of 4-substituted dioxolanes

Specifications

CAS 99569-11-6
Density 1.203 g/mL (at 25°C (literature))
Boiling Point 192°C to 193°C (lit.)
Molecular Formula C4H8O3
Refractive Index n20/D 1.451 (literature); n20/D 1.451
Linear Formula C4H8O3
MDL Number MFCD10039829
Quantity 500 mL
Molecular Weight (g/mol) 104.1
Percent Purity ≥98.0% (GC)
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