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Cayman Chemical GlycIdyl PalmItate 100mg

Supplier: Cayman Chemical 9003681100 MG

An inhibitor of heteromeric Kir4.1/5.1 channels (IC50 0.24 UM) selective for Kir4.1/5.1 channels over a variety of homomeric Kir channels including Kir4.1 (IC50 >10 UM) as well as heteromeric Kir3.1/3.2 Kir3.1/3.4 Kir6.2/SUR1 and Kir6.1/SUR2b channels at 30 UM but does inhibit the voltage-gated potassium channel Kv1.1 (IC50 6.4 UM) does not inhibit diuresis in mice at 30 and 100 mg/kg due to low oral bioavailability and high hepatic clearance
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