Glycine tert-butyl ester, 97%

Catalog No.	Quantity
AAL1625803	1 g
AAL1625806	5 g

Catalog No. AAL1625803 Supplier Thermo Scientific Chemicals Supplier No. L1625803

Description

CAS: 6456-74-2 | C6H13NO2 | 131.175 g/mol

Glycine tert-butyl ester is used in the preparation of Schiff base by reacting with benzophenone. The resultant Schiff base undergoes asymmetric alkylation with arylmethyl bromides in the presence of O-allyl-N-(9-anthracenylmethyl)cinchonidinium bromide as chiral phase transfer catalyst to give guanidine-containing pentacyclic compound.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Glycine tert-butyl ester is used in the preparation of Schiff base by reacting with benzophenone. The resultant Schiff base undergoes asymmetric alkylation with arylmethyl bromides in the presence of O-allyl-N-(9-anthracenylmethyl)cinchonidinium bromide as chiral phase transfer catalyst to give guanidine-containing pentacyclic compound.

Solubility
Miscible with acetone and methanol. Slightly miscible with ehtanol. Immiscible with water.

Notes
Air sensitive. Store in a cool place. Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 6456-74-2
• Molecular Formula: C6H13NO2
• Molecular Weight (g/mol): 131.175
• MDL Number: MFCD00038194
• InChI Key: SJMDMGHPMLKLHQ-UHFFFAOYSA-N
• Synonym: tert-butyl glycinate, glycine tert-butyl ester, glycine, 1,1-dimethylethyl ester, tert-butyl aminoacetate, h-gly-otbu, t-butyl glycinate, glycin-tert-butyl ester, 1,1-dimethylethyl glycinate, glycine t-butyl ester, aminoacetic acid tert-butyl ester
• PubChem CID: 151417
• IUPAC Name: tert-butyl 2-aminoacetate
• SMILES: CC(C)(C)OC(=O)CN

• Boiling Point: 29°C to 31°C (2mmHg)
• Refractive Index: 1.424
• Beilstein: 2039000
• Solubility Information: Miscible with acetone and methanol. Slightly miscible with ehtanol. Immiscible with water.
• Density: 0.96
• Quantity: 1 g
• Formula Weight: 131.18
• Percent Purity: 97%
• Sensitivity: Air sensitive
• Chemical Name or Material: Glycine tert-butyl ester

Safety and Handling

TSCA	No
Recommended Storage	Keep cold; Store under Argon

SDS

RUO – Research Use Only