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Medchemexpress LLC Glycocholic acid | 475-31-0 | 465.62 | 50 G
SDP

Catalog No. 5000415688
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Glycocholic acid is an endogenous bile acid that exhibits anticancer activity. It targets both pump resistance-related and non-pump resistance-related pathways, enhancing the cytotoxicity of drugs like epirubicin by increasing their intracellular accumulation and absorption, and intensifying epirubicin-induced apoptosis.

  • Exhibits anticancer activity
  • Enhances cytotoxicity and absorption of epirubicin
  • Intensifies epirubicin-induced apoptosis
  • Modulates drug resistance pathways (MDR1, MRP1, MRP2, P-gp)
  • Regulates apoptosis-related pathways (Bcl-2, Bax, p53, caspase-9, -3)
  • Agonist activity at human TGR5
  • Inhibits E217betaG uptake in MRP4-expressing cells

Catalog No. 50-004-15688 Supplier Medchemexpress LLC Supplier No. HYN142350G
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Glycocholic acid is an endogenous bile acid that exhibits anticancer activity. It targets both pump resistance-related and non-pump resistance-related pathways, enhancing the cytotoxicity of drugs like epirubicin by increasing their intracellular accumulation and absorption, and intensifying epirubicin-induced apoptosis.

  • Exhibits anticancer activity
  • Enhances cytotoxicity and absorption of epirubicin
  • Intensifies epirubicin-induced apoptosis
  • Modulates drug resistance pathways (MDR1, MRP1, MRP2, P-gp)
  • Regulates apoptosis-related pathways (Bcl-2, Bax, p53, caspase-9, -3)
  • Agonist activity at human TGR5
  • Inhibits E217betaG uptake in MRP4-expressing cells

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