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Cayman Chemical GlycoursodeoxycholIc ACD 250mg

Supplier: Cayman Chemical 21698250 MG

A P-gp inhibitor inhibits the efflux of [3H]vinblastine by ABCB1 in Caco-2 colon cancer cells (EC50 0 05 UM) inhibits the efflux of rhodamine-123 and calcein-AM by BCRP and MRP1 in MDCK cells (EC50s 73 and 9 3 UM respectively) enhances growth inhibition of MCF-7/ADR breast cancer cells at 2 or 20 UM when used in combination with doxorubicin in vitro but does not alter the effectiveness of doxorubicin on growth inhibition in Caco-2 cells increases phosphorylation of p38 and JNK in Caco-2 cells and MCF-7/ADR cells when used at a concentration of 20 UM
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