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Medchemexpress LLC GlyT1 Inhibitor 1 | 1820934-93-7 | 98.59% | 387.43 | 10 MG
SDP

Catalog No. 5000438379
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GlyT1 Inhibitor 1 is a potent and selective GlyT1 inhibitor with an IC50 of 38 nM for rGlyT1. It also demonstrates antipsychotic activity and in vivo efficacy in a rat novel object recognition (NOR) assay after oral dosing at 0.1, 1, and 3 mg/kg.

  • Potent and selective GlyT1 inhibitor
  • IC50: 38 nM for rGlyT1
  • Antipsychotic activity
  • In vivo efficacy in rat novel object recognition (NOR) assay
  • Appearance: Solid, White to off-white
  • Formula: C22H21N5O2
  • Shipping: Room temperature in continental US; may vary elsewhere
  • Storage: Powder at -20°C for 3 years or 4°C for 2 years; In solvent at -80°C for 6 months or -20°C for 1 month
  • Solubility (In Vitro): DMSO : 25 mg/mL (64.53 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Catalog No. 50-004-38379 Supplier Medchemexpress LLC Supplier No. HY11243210MG
May include imposed supplier surcharges.
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GlyT1 Inhibitor 1 is a potent and selective GlyT1 inhibitor with an IC50 of 38 nM for rGlyT1. It also demonstrates antipsychotic activity and in vivo efficacy in a rat novel object recognition (NOR) assay after oral dosing at 0.1, 1, and 3 mg/kg.

  • Potent and selective GlyT1 inhibitor
  • IC50: 38 nM for rGlyT1
  • Antipsychotic activity
  • In vivo efficacy in rat novel object recognition (NOR) assay
  • Appearance: Solid, White to off-white
  • Formula: C22H21N5O2
  • Shipping: Room temperature in continental US; may vary elsewhere
  • Storage: Powder at -20°C for 3 years or 4°C for 2 years; In solvent at -80°C for 6 months or -20°C for 1 month
  • Solubility (In Vitro): DMSO : 25 mg/mL (64.53 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

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