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Medchemexpress LLC GNE-131 | 1629063-81-5 | 98.2% | 442.57 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY11227910MM/1ML

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GNE-131 is a potent and selective inhibitor of human sodium channels, specifically targeting NaV1.7 with an IC50 of 3 nM. This compound has demonstrated excellent potency and good in vitro metabolic stability. It also exhibits low in vivo clearance in mouse, rat, and dog models, along with excellent efficacy in a transgenic mouse model of induced pain.

  • Potent and selective sodium channel inhibition.
  • Good metabolic stability in laboratory settings.
  • Effective in pain models.
  • Low clearance in multiple animal species.

Catalog No. 50-004-38177


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