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Medchemexpress LLC GNE-149 | 1953132-75-6 | 99.2% | C28H33F4N3O | 25 MG
SDP

Catalog No. 5000356614
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GNE-149 is an orally bioavailable full antagonist of estrogen receptor α (ERα) and a selective estrogen receptor degrader (SERD). It can be used for breast cancer research, exhibiting antiproliferative activity in MCF7 and T47D cells, and inducing ERα degradation. It also demonstrates efficacy in an MCF7 xenograft mouse model.

  • Full antagonist of estrogen receptor α (ERα)
  • Selective estrogen receptor degrader (SERD)
  • Exhibits antiproliferative activity in MCF7 and T47D cells
  • Induces ERα degradation
  • Favorable pharmacokinetic profile with oral bioavailability in various models
  • Solid, white to light yellow appearance

Catalog No. 50-003-56614 Supplier Medchemexpress LLC Supplier No. 25MGHY145341
May include imposed supplier surcharges.
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GNE-149 is an orally bioavailable full antagonist of estrogen receptor α (ERα) and a selective estrogen receptor degrader (SERD). It can be used for breast cancer research, exhibiting antiproliferative activity in MCF7 and T47D cells, and inducing ERα degradation. It also demonstrates efficacy in an MCF7 xenograft mouse model.

  • Full antagonist of estrogen receptor α (ERα)
  • Selective estrogen receptor degrader (SERD)
  • Exhibits antiproliferative activity in MCF7 and T47D cells
  • Induces ERα degradation
  • Favorable pharmacokinetic profile with oral bioavailability in various models
  • Solid, white to light yellow appearance

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