Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000437866

Medchemexpress LLC GNE-371 | 1926986-36-8 | 98.06% | 431.49 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY112803100MG

Encompass_Preferred

GNE-371 is a potent and selective chemical probe designed to target the second bromodomains of human transcription-initiation-factor TFIID subunit 1 and transcription-initiation-factor TFIID subunit 1-like. It demonstrates an IC50 of 10 nM for TAF1(2).

  • Potent and selective chemical probe for TAF1(2) bromodomains.
  • Binds TAF1(2) with an IC50 of 10 nM.
  • Maintains excellent selectivity over other bromodomain-family members.
  • Active in cellular-TAF1(2) target-engagement assay (IC50=38 nM).
  • Exhibits anti-proliferative synergy with the BET inhibitor JQ1.
  • Supports use in mechanistic and target-validation studies.

Catalog No. 50-004-37866


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.