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Cayman Chemical Gngerenon A 10mg
Supplier: Cayman Chemical 3684110 MG
A diarylheptanoid and polyphenol with diverse biological activities; inhibits tyrosinase (IC50 = 9.4 µM for the mushroom enzyme); scavenges DPPH radicals in a cell-free assay (IC50 = 12.6 µM); inhibits JAK2 and p70S6K1 at 5 and 10 µM; selectively decreases the viability of ionizing radiation-induced senescent WI38 fibroblasts over proliferating fibroblasts at 20 µM; prevents increases in body weight but does not affect caloric intake in a mouse model of high-fat diet-induced obesity at 50 mg/kg; decreases tumor weight in an HCT116 colon cancer mouse xenograft model at 5 and 20 mg/kg
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