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Cayman Chemical GnglIosIde GM1ovInamo 50mg
Supplier: Cayman Chemical 3154950 MG
A ganglioside; enriched in lipid rafts; associates with growth factor receptors and is required for TrkA expression on the cell surface; interacts with other proteins to increase calcium influx, affecting various calcium-dependent processes, including inducing neuronal outgrowth during differentiation; acts as a receptor for cholera toxin and the heat-labile enterotoxin from E. coli; accumulates in neurons in ganglioside GM1 gangliosidosis; levels are decreased in the substantia nigra pars compacta in postmortem brain from patients with Parkinson’s disease
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