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Cayman Chemical GnoderIc AcId A 50mg
Supplier: Cayman Chemical 2667450 MG
A triterpene with diverse biological activities; reduces cell viability, expression SOD1, SOD2, and SOD3, and production of ROS in PC3 prostate cancer cells; inhibits LPS-induced activation of NF-κB, release of TNF-α, IL-1β, and IL-6, and mitochondrial activity in primary mouse cortical microglia; reduces lung MPO activity, neutrophil infiltration, and NF-κB signaling, as well as BALF levels of TNF-α, IL-1β, and IL-6 in a mouse model of LPS-induced lung injury at 20 and 40 mg/kg; reduces weight gain and hepatic lipid accumulation and improves insulin sensitivity in a mouse model of high-fat diet-induced obesity
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