Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Apexbio Technology LLC Golgicide A 1139889-93-2 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B13855.1
Golgicide A is a reversible small-molecule inhibitor targeting the guanine nucleotide exchange factor GBF1 GBF1 functions as an ArfGEF facilitating Arf1 activation and COPI recruitment at the cis-Golgi membranes essential for Golgi structure maintenance and protein transport regulation Golgicide A disrupts Golgi morphology leading to dispersion of Golgi markers and altered COPI localization In cellular assays Golgicide A inhibits shiga toxin-mediated protein synthesis with an IC50 of approximately 3 3 M in Vero cells and impairs retrograde toxin trafficking and secretory protein transport Additionally Golgicide A is applied in HCV research to reduce viral RNA replication and alter NS5A localization causing accumulation of viral particles in infected cells
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?