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Medchemexpress LLC Goserelin (acetate) | 145781-92-6 | 99.9% | 1329.46 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY13673A50MG

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Goserelin acetate (ICI-118630 acetate) is a decapeptide analogue of gonadotropin-releasing hormone (GnRH/LHRH) that acts as a GnRH agonist. It can be used for the research of breast cancer, epithelial ovarian cancer, and prostate cancer.

  • Promotes EOC cell apoptosis at concentrations of 1 nM-1 mM over 48-72 hours.
  • Regulates expression of human apoptosis-related genes in SKOV3-ip cells at 100 μM over 24-72 hours.
  • Induces EOC cell apoptosis by upregulating FOXO1 through the PI3K/AKT signaling pathway at 100 μM over 24-72 hours.
  • Significantly increases the proportion of apoptotic cells in subcutaneous xenograft tumors in vivo.

Catalog No. 50-003-48146


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