Gossypol, 98+%

Description

Lipophilic agent derived from cottonseed | CAS: 303-45-7 | C30H30O8 | 518.56 g/mol

Gossypol acts as an inhibitor for several dehydrogenase enzymes. Gossypol has also long been known to possess antimalarial properties. Gossypol provided reliable contraception. gossypol provokes infertility and causes spermatogenesis. Gossypol is used as an active antifertility agent in a variety of male animals, including mice, rats, hamsters, monkeys, rabbits, and bulls.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Gossypol acts as an inhibitor for several dehydrogenase enzymes. Gossypol has also long been known to possess antimalarial properties. Gossypol provided reliable contraception. gossypol provokes infertility and causes spermatogenesis. Gossypol is used as an active antifertility agent in a variety of male animals, including mice, rats, hamsters, monkeys, rabbits, and bulls.

Solubility
Soluble in 100%ethanol (25 mg/ml), DMF (25 mg/ml), acetone, DMSO (25 mM), methanol (2 mg/ml), ether, chloroform, sodium carbonate, and dilute aqueous solutions of ammonia . Insoluble in water. Gossypol is a male antifertility agent with antispermatogenic activity and has been shown to contain antitumor, anitviral, and antioxidant properties.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

Specifications

Chemical Identifiers

• CAS: 303-45-7
• Molecular Formula: C30H30O8
• Molecular Weight (g/mol): 518.56
• MDL Number: MFCD00017352
• InChI Key: QBKSWRVVCFFDOT-UHFFFAOYSA-N
• Synonym: gossypol, --gossypol, +-gossypol, pogosin, tash 1, racemic-gossypol, r---gossypol, r-gossypol, +--gossypol, +/--gossypol
• PubChem CID: 3503
• ChEBI: CHEBI:28584
• SMILES: CC(C)C1=C(O)C(O)=C(C=O)C2=C(O)C(=C(C)C=C12)C1=C(O)C2=C(C=O)C(O)=C(O)C(C(C)C)=C2C=C1C

• Color: Yellow to Brown
• Quantity: 250 mg
• Merck Index: 14,4528
• Solubility Information: Soluble in 100%ethanol (25mg/ml),DMF (25mg/ml),acetone,DMSO (25 mM),methanol (2mg/ml),ether,chloroform,sodium carbonate,and dilute aqueous solutions of ammonia . Insoluble in water. Gossypol is a male antifertility agent with antispermatogenic activity and has been shown to contain antitumor,anitviral,and antioxidant properties.
• IUPAC Name: 1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-5,5'-bis(propan-2-yl)-[2,2'-binaphthalene]-8,8'-dicarbaldehyde
• Formula Weight: 518.56
• Percent Purity: ≥98%
• Physical Form: Powder
• Chemical Name or Material: Gossypol

Safety and Handling

Hazard Category	H302-H341-H361
Hazard Statement	GHS H Statement H341-H361-H302 Suspected of causing genetic defects. Suspected of damaging fertility or the unborn child. Harmful if swallowed.
Precautionary Statement	P201-P202-P264b-P270-P281-P301+P312-P308+P313-P330-P501c
RTECSNumber	DU3100000
TSCA	No
Recommended Storage	Store at -20°C

SDS

RUO – Research Use Only