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Medchemexpress LLC Gossypol (acetic acid) | 12542-36-8 | 99.75% | 578.61 | 500 MG
SDP

Catalog No. 5000386387
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Gossypol acetic acid binds to Bcl-xL protein with a Ki of 0.5-0.6 μM and Bcl-2 protein with a Ki of 0.2-0.3 mM. It is a natural product isolated from cottonseeds and roots and has been studied as an anticancer agent. The racemic form of Gossypol has been tested in several clinical trials and is well tolerated. The (-)-Gossypol enantiomer shows greater growth inhibition relative to (±)-Gossypol than (+)-Gossypol in UM-SCC-6 and UM-SCC-14A cell lines.

  • Binds to Bcl-xL protein with a Ki of 0.5-0.6 μM.
  • Binds to Bcl-2 protein with a Ki of 0.2-0.3 mM.
  • A natural product isolated from cottonseeds and roots.
  • The racemic form has been evaluated in clinical trials and is well tolerated.
  • The (-)-Gossypol enantiomer demonstrates greater growth inhibition compared to other forms in tested cell lines.

Catalog No. 50-003-86387 Supplier Medchemexpress LLC Supplier No. HY17510500MG
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Gossypol acetic acid binds to Bcl-xL protein with a Ki of 0.5-0.6 μM and Bcl-2 protein with a Ki of 0.2-0.3 mM. It is a natural product isolated from cottonseeds and roots and has been studied as an anticancer agent. The racemic form of Gossypol has been tested in several clinical trials and is well tolerated. The (-)-Gossypol enantiomer shows greater growth inhibition relative to (±)-Gossypol than (+)-Gossypol in UM-SCC-6 and UM-SCC-14A cell lines.

  • Binds to Bcl-xL protein with a Ki of 0.5-0.6 μM.
  • Binds to Bcl-2 protein with a Ki of 0.2-0.3 mM.
  • A natural product isolated from cottonseeds and roots.
  • The racemic form has been evaluated in clinical trials and is well tolerated.
  • The (-)-Gossypol enantiomer demonstrates greater growth inhibition compared to other forms in tested cell lines.

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