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Medchemexpress LLC Gozanertinib | 1226549-49-0 | 98.4% | 50 MG
SDP

Supplier:  Medchemexpress LLC HY12877850MG

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Gozanertinib is an orally active furanopyrimidine-based EGFR inhibitor with IC50s of 15 nM for EGFRWT and 48 nM for EGFRL858R/T790M. It can occupy the ATP-binding site and demonstrates significant antitumor efficacy. This compound is intended for research use only.

  • Orally active EGFR inhibitor
  • IC50 of 15 nM for EGFRWT
  • IC50 of 48 nM for EGFRL858R/T790M
  • Occupies ATP-binding site
  • Demonstrates significant antitumor efficacy
  • Molecular weight: 533.62
  • Formula: C32H31N5O3
  • Appearance: solid, off-white to light yellow
  • Inhibits HCC827, H1975, and A431 cell lines
  • Reduces phosphorylated EGFR in a dose-dependent manner

Catalog No. 50-003-41344


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