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Medchemexpress LLC GP531 | 142344-87-4 | 347.37 | 50 MG
Supplier: Medchemexpress LLC HYU0011650MG
GP531 is a potent, second-generation adenosine regulating agent. It is pharmacologically silent under basal conditions but increases localized endogenous adenosine during ischemia. It is effective at lower doses in reducing ischemic/reperfusion injury severity without inducing adverse hemodynamic effects.
- Reduces infarct size and anatomic no-reflow zone in rabbits
- Effective at lower doses in reducing ischemic/reperfusion injury severity
- Does not induce adverse hemodynamic effects like bradycardia and hypotension
- Decreases left ventricular end-diastolic pressure, end-diastolic volume, end-systolic volume, and end-diastolic wall stress in dogs with heart failure
- Increases left ventricular ejection fraction without increasing myocardial oxygen consumption
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