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Eurofins Discoverx PathHunter GPR120L Total Internalization HEK 293 Cell Line, 2 vials. (93-0801C1)

Supplier:  Eurofins Discoverx 930801C1

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The PathHunter GPR120L Total Internalization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This cell line uses EFC technology to measure ligand-induced internalization of GPR120L via detection of localization to the early endosome. The included cell line overexpresses EA-tagged GPR120L and a ProLink-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the GPR120L receptor to the early endosome leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.

Catalog No. 50-200-1324


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