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Medchemexpress LLC GPRP acetate | 157009-81-9 | 98.9% | 485.53 | 25 MG
Supplier: Medchemexpress LLC 25MGHYP0074A
GPRP acetate (Gly-Pro-Arg-Pro acetate) is a fibrin polymerization inhibitor that blocks the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa). This compound enhances free thrombin generation and has demonstrated significant therapeutic potential in animal models, alleviating DSS-induced colitis by improving body weight loss and mortality.
- Inhibits fibrin polymerization.
- Targets platelet membrane glycoprotein IIb/IIIa complex.
- Increases free thrombin generation.
- Alleviates DSS-induced colitis in animal models.
- Reduces DSS-induced shortening of colon length.
- Decreases tissue damage and infiltration of inflammatory cells.
- Lowers levels of inflammatory cytokines in colitis mice.
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