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BPS Bioscience Inc GR-GAL4 Luciferase Reporter Jurkat Cell Line, 2 vials
Supplier: BPS Bioscience Inc 78525
The GR-GAL4 Luciferase Reporter Jurkat Cell Line is specifically designed for the detection of glucocorticoid receptor activation. This stably integrated reporter cell line utilizes an engineered transcription factor that combines the glucocorticoid receptor ligand binding domain with the GAL4 DNA binding domain, enabling the expression of firefly luciferase under a multimerized GAL4 UAS. The cell line is confirmed to respond to dexamethasone and inhibited by mifepristone, providing a reliable method to study glucocorticoid signaling while minimizing interference from other nuclear receptor pathways.
- Validated for responsiveness to dexamethasone stimulation
- Inhibition validated by mifepristone
- Responsive in glucocorticoid receptor signaling assays
- Features low cross-reactivity with other nuclear receptors
- Comes in a format of 2 vials
- Designed for research use only
- Limited Use License applicable
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