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Medchemexpress LLC GR127935 hydrochloride | 148642-42-6 | 99.4% | 534.05 g/mol | C29H32ClN5O3 | 5 MG
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Supplier:  Medchemexpress LLC HY1007945MG

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GR127935 hydrochloride is a potent, selective antagonist of 5-HT1B and 5-HT1D serotonin receptors used in neuroscience and pharmacology research. It exhibits high affinity (pKi ≈ 8.5) and strong selectivity versus other serotonin subtypes, making it suitable for receptor pharmacology, signaling studies, and in vitro or in vivo applications.

  • Potent 5-HT1B/1D receptor antagonist (pKi ≈ 8.5).
  • Greater than 100-fold selectivity over 5-HT1A, 5-HT2A, and 5-HT2C.
  • High purity (≈99.4%).
  • White to off-white solid suitable for small-scale research.
  • Stable when stored as recommended (solid at -20°C; solutions cold-stored).

Catalog No. 50-002-13587


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