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Medchemexpress LLC GRA Ex-25 | 307983-31-9 | 99.1% | C29H36F3N3O5 | 1 ML
SDP

Catalog No. 5000357931
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GRA Ex-25 is an inhibitor of the glucagon receptor, with an IC50 of 56 nM for rat glucagon receptors and 55 nM for human glucagon receptors. It binds to the human glucagon receptor (h-GlucRbind) with a Ki of 63 nM and demonstrates moderate glucagon-induced adenylate cyclase inhibition (h-GlucRcyclase) with a Ki of 254 nM.

  • Significantly reduces blood glucose levels in a rat model.
  • Directly inhibits glucagon-stimulated hepatic glucose output.
  • Suitable for research applications.

Catalog No. 50-003-57931 Supplier Medchemexpress LLC Supplier No. HY5067510MM/1ML
May include imposed supplier surcharges.
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GRA Ex-25 is an inhibitor of the glucagon receptor, with an IC50 of 56 nM for rat glucagon receptors and 55 nM for human glucagon receptors. It binds to the human glucagon receptor (h-GlucRbind) with a Ki of 63 nM and demonstrates moderate glucagon-induced adenylate cyclase inhibition (h-GlucRcyclase) with a Ki of 254 nM.

  • Significantly reduces blood glucose levels in a rat model.
  • Directly inhibits glucagon-stimulated hepatic glucose output.
  • Suitable for research applications.

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