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Cayman Chemical GramIcIdIn A 10mg

Supplier: Cayman Chemical 2638410 MG
A channel-forming ionophore; a peptide component of the antibiotic gramicidin; forms channels in model membranes that are permeable to monovalent cations, protons, and water; induces degradation of HIF-1α in HEK293 cells and reduces growth in a human renal cell carcinoma mouse xenograft model at 0.22 mg/kg three times per week; reduces viral yield in WI-38 fibroblasts inoculated with isolates of HSV-1 and HSV-2 (IC50 = 0.3 UG/ml for all); commonly been used to study channel structure and function
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