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Apexbio Technology LLC Griseofulvin 126-07-8 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B36805.1
Griseofulvin is an antifungal antibiotic known to inhibit fungal growth by interfering with microtubule polymerization thereby disrupting mitotic spindle formation and cellular division Through binding to tubulin it stabilizes microtubule structures preventing their normal assembly and leading to impaired fungal cell replication Experimentally Griseofulvin has been frequently utilized to study microtubule dynamics mitotic processes and antifungal mechanisms in research settings involving medically relevant fungi including dermatophytes Reported IC50 values for Griseofulvin range approximately from 5 to 20 M depending on fungal strains and conditions tested serving as a guideline for establishing antifungal assays and investigating fungal response mechanisms in vitro
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