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Apexbio Technology LLC GSK 2837808A 1445879-21-9 5mg
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Catalog No. 502240154
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GSK 2837808A (CAS 1445879-21-9) is a small-molecule inhibitor that selectively targets lactate dehydrogenase A (LDHA) exhibiting potent inhibitory activity with IC50 values of 1 9 nM for LDHA and 14 nM for LDHB In cellular studies GSK 2837808A at 10 M reduced glucose consumption in Snu398 hepatocellular carcinoma cells but not in HepG2 cells indicating cell line-specific metabolic effects Pharmacokinetic analysis in rodents demonstrated rapid clearance following intravenous administration and minimal systemic exposure after oral dosing GSK 2837808A serves as a valuable tool for investigating LDHA function and metabolic regulation in cancer research

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Catalog No. 50-224-0154 Supplier Apexbio Technology LLC Supplier No. B49295
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GSK 2837808A (CAS 1445879-21-9) is a small-molecule inhibitor that selectively targets lactate dehydrogenase A (LDHA) exhibiting potent inhibitory activity with IC50 values of 1 9 nM for LDHA and 14 nM for LDHB In cellular studies GSK 2837808A at 10 M reduced glucose consumption in Snu398 hepatocellular carcinoma cells but not in HepG2 cells indicating cell line-specific metabolic effects Pharmacokinetic analysis in rodents demonstrated rapid clearance following intravenous administration and minimal systemic exposure after oral dosing GSK 2837808A serves as a valuable tool for investigating LDHA function and metabolic regulation in cancer research

This item is not returnable. View return policy
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