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Apexbio Technology LLC GSK 5959 901245-65-6 10mg
SDP

Catalog No. 5000091131
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GSK 5959 (CAS 901245-65-6) is a selective small-molecule inhibitor targeting the bromodomain of BRPF1 (bromodomain and PHD finger-containing protein 1) By binding specifically to the BRPF1 bromodomain GSK 5959 disrupts its interaction with acetylated histones thereby modulating associated epigenetic regulatory pathways In vitro studies report an IC50 of 80 nM for inhibition of BRPF1 bromodomain activity Due to its favorable cell permeability GSK 5959 is widely utilized in research investigating BRPF1-dependent mechanisms of gene expression and in the exploration of epigenetic contributions to disease models

Catalog No. 50-000-91131 Supplier Apexbio Technology LLC Supplier No. B491610
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GSK 5959 (CAS 901245-65-6) is a selective small-molecule inhibitor targeting the bromodomain of BRPF1 (bromodomain and PHD finger-containing protein 1) By binding specifically to the BRPF1 bromodomain GSK 5959 disrupts its interaction with acetylated histones thereby modulating associated epigenetic regulatory pathways In vitro studies report an IC50 of 80 nM for inhibition of BRPF1 bromodomain activity Due to its favorable cell permeability GSK 5959 is widely utilized in research investigating BRPF1-dependent mechanisms of gene expression and in the exploration of epigenetic contributions to disease models

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