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Abcam GSK-J1, H3K27 histone demethylase inhibitor, 50MG
Supplier: Abcam AB14439650MG
MW 389.4 Da, Purity >99%. Potent and selective H3K27 histone demethylase inhibitor (IC₅₀ = 60 nM, JMJD3). Inhibits UTX. Some activity for the H3K4me3/2/1 demethylases Jarid1b and Jarid1c (IC₅₀ values are 950 nM and 1.76 μM, respectively). No significant inhibitory activity against 100 protein kinases at a concentration of 30 μM. Anti-inflammatory effects.
The product is subject to the following: Abcam Restricted Use Statement
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