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Apexbio Technology LLC GSK1349572 sodiuM salt 1051375-19-9 10mg
Supplier: Apexbio Technology LLC B585610
GSK1349572 sodium salt (CAS 1051375-19-9) is a small-molecule inhibitor targeting HIV integrase It is designed to inhibit the integrase-mediated strand transfer process thereby blocking the integration of viral DNA into the host genome GSK1349572 sodium salt exerts its biological activity primarily through interaction with the enzyme s two-metal ion catalytic site inhibiting strand transfer In in vitro studies GSK1349572 sodium salt demonstrates potent antiviral inhibition with a protein-adjusted IC50 of approximately 38 nM in the presence of 100% human serum Based on these pharmacological properties GSK1349572 sodium salt holds research potential in antiviral studies evaluation of resistance profiles and drug development of integrase inhibitors for HIV therapy
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