Apexbio Technology LLC GSK1349572 sodiuM salt 1051375-19-9 5mg

Supplier:  Apexbio Technology LLC B58565

GSK1349572 sodium salt (CAS 1051375-19-9) is a small-molecule inhibitor targeting HIV integrase It is designed to inhibit the integrase-mediated strand transfer process thereby blocking the integration of viral DNA into the host genome GSK1349572 sodium salt exerts its biological activity primarily through interaction with the enzyme s two-metal ion catalytic site inhibiting strand transfer In in vitro studies GSK1349572 sodium salt demonstrates potent antiviral inhibition with a protein-adjusted IC50 of approximately 38 nM in the presence of 100% human serum Based on these pharmacological properties GSK1349572 sodium salt holds research potential in antiviral studies evaluation of resistance profiles and drug development of integrase inhibitors for HIV therapy

Catalog No. 50-000-95598