Learn More
Cayman Chemical GSK1904529A 10mg

Supplier: Cayman Chemical 2915510 MG
A dual InsR and IGF-1R kinase inhibitor (IC50s = 25 and 27 nM, respectively, in a cell-free assay); selectively inhibits InsR and IGF-1R kinases over a panel of 45 serine/threonine and tyrosine kinases (IC50s = >1 µM for all); decreases proliferation of 13 cancer cell lines including multiple myeloma, sarcoma, colon, and breast cancer cells (IC50s = 35-189 nM) in a panel of 35 cell lines; reduces tumor growth in NIH3T3-LISN, COLO 205, HT-29, and BxPC3 mouse xenograft models at 30 mg/kg for 21 days
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.