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Apexbio Technology LLC GSK2636771 1372540-25-4 10mM (in 1mL DMSO)
SDP

Supplier:  Apexbio Technology LLC B21865.1

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GSK2636771 (CAS 1372540-25-4) is a selective inhibitor targeting the p110 isoform of class I phosphoinositide 3-kinase (PI3K) PI3Ks comprise catalytic subunits p110 and which mediate signaling cascades critical for cellular proliferation and survival Specifically GSK2636771 reduces AKT phosphorylation in breast cancer cell lines leading to diminished cellular viability In PTEN-deficient endometrioid endometrial cancer (EEC) cell lines combination with the p110 inhibitor A66 enhances inhibition of cell growth This compound serves as a research tool for investigating PI3K signaling and potential cancer therapeutic strategies

Catalog No. 50-000-62082


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