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Medchemexpress LLC GSK2879552 dihydrochloride | 1902123-72-1 | 99.8% | 437.40 | 50 MG
SDP

Catalog No. 5000387806
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GSK2879552 dihydrochloride is an orally active, selective, and irreversible inhibitor of lysine specific demethylase 1 (LSD1/KDM1A), which possesses potential antineoplastic activity. It is intended for research use only and not for patient use.

  • Orally active, selective, and irreversible inhibitor
  • Inhibits KDM1A histone demethylase activity
  • Induces differentiation of sorafenib-resistant cells
  • Attenuates stemness properties
  • Depresses the transcription of Wnt antagonists
  • Downregulates β-catenin signaling activity in sorafenib-resistant cells
  • Inhibits cell proliferation in SCLC and AML cell lines
  • Exhibits tumor growth inhibition in SCLC xenograft bearing mice
  • Potential antineoplastic activity
  • For research use only

Catalog No. 50-003-87806 Supplier Medchemexpress LLC Supplier No. HY18632A50MG
May include imposed supplier surcharges.
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GSK2879552 dihydrochloride is an orally active, selective, and irreversible inhibitor of lysine specific demethylase 1 (LSD1/KDM1A), which possesses potential antineoplastic activity. It is intended for research use only and not for patient use.

  • Orally active, selective, and irreversible inhibitor
  • Inhibits KDM1A histone demethylase activity
  • Induces differentiation of sorafenib-resistant cells
  • Attenuates stemness properties
  • Depresses the transcription of Wnt antagonists
  • Downregulates β-catenin signaling activity in sorafenib-resistant cells
  • Inhibits cell proliferation in SCLC and AML cell lines
  • Exhibits tumor growth inhibition in SCLC xenograft bearing mice
  • Potential antineoplastic activity
  • For research use only

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