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Medchemexpress LLC GSK2945 hydrochloride | 00-00-0 | 99.7% | 457.80 g/mol | C20H19Cl3N2O2S | 5 MG
Supplier: Medchemexpress LLC HY117147A5MG
GSK2945 hydrochloride is the hydrochloride salt of a small-molecule antagonist of the nuclear receptor Rev-erbα, supplied for preclinical research. It has reported EC50 values of 21.5 μM (mouse) and 20.8 μM (human) and has been used to increase CYP7A1 levels and modulate cholesterol metabolism.
- High chemical purity (99.7%).
- Solid form suitable for storage at 4°C; in solution store under nitrogen at -80°C (6 months) or -20°C (1 month).
- Soluble in DMSO (~20.83 mg/mL); in vivo formulations and protocols are available for suspension or clear solution preparations.
- Activity: Rev-erbα antagonist with reported EC50 around 21 μM in cell-based assays.
- Provided for research use with supporting assay and formulation data.
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