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Selleck Chemical LLC GSK690693 50mg 937174-76-0
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Supplier:  Selleck Chemical LLC S111350MG

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GSK690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM in cell-free assays, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. GSK690693 also potently inhibits AMPK and DAPK3 from the CAMK family with IC50 of 50 nM and 81 nM, respectively. GSK690693 affects Unc-51-like autophagy activating kinase 1 (ULK1) activity, robustly inhibits STING-dependent IRF3 activation. Phase 1. *For Research & Development use only.  Product is not intended for drug, household, or human consumption.

Catalog No. 50-854-4


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