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Medchemexpress LLC GsMTx4 TFA | 99.9% | 4095.84 (free base) | 5 MG
Supplier: Medchemexpress LLC HYP1410A5MG
GsMTx4 TFA is a spider venom peptide designed to selectively inhibit cationic-permeable mechanosensitive channels (MSCs) within the Piezo and TRP channel families. It acts as a pharmacological tool to investigate the role of these excitatory MSCs in both normal physiological processes and various pathological conditions.
- Selectively inhibits cationic-permeable mechanosensitive channels (MSCs) belonging to Piezo and TRP families.
- Blocks cation-selective stretch-activated channels in various cell types.
- Attenuates lysophosphatidylcholine-induced astrocyte toxicity and microglial reactivity.
- Neuroprotective in the cerebral cortex.
- Reduces mechanical allodynia in models of inflammation and sciatic nerve injury.
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