ABclonal Technology GSTA4 Rabbit mAb

Supplier:  ABclonal Technology A2355520UL

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families These enzymes are involved in cellular defense against toxic carcinogenic and pharmacologically active electrophilic compounds At present eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified alpha kappa mu omega pi sigma theta and zeta This gene encodes a glutathione S-tranferase belonging to the alpha class The alpha class genes which are located in a cluster on chromosome 6 are highly related and encode enzymes with glutathione peroxidase activity that function in the detoxification of lipid peroxidation products Reactive electrophiles produced by oxidative metabolism have been linked to a number of degenerative diseases including Parkinson s disease Alzheimer s disease cataract formation and atherosclerosis

Catalog No. 50-000-05029