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Medchemexpress LLC Guanfacine hydrochloride | 29110-48-3 | 99.9% | 282.55 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY1741610MM/1ML

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Guanfacine hydrochloride is an orally active and blood-brain barrier permeable noradrenergic α2A agonist that shows high selectivity for the α2A receptor subtype. It has been shown to induce hypotension and sedation, and is used in research for various prefrontal cortex (PFC) cognitive disorders, including Tourette's syndrome and attention deficit hyperactivity disorder (ADHD).

  • Orally active and blood-brain barrier permeable.
  • Highly selective noradrenergic α2A agonist.
  • Increases delay-related neuronal firing for working memory.
  • Improves PFC cognitive function by inhibiting cAMP production and strengthening PFC networks.
  • Enhances PFC working memory and improves impulse control in in vivo studies.
  • Soluble in DMSO (≥ 30 mg/mL) and water (20 mg/mL).
  • Applicable in research for conditions like Tourette's syndrome and ADHD.

Catalog No. 50-003-86058


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