Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC Guanfacine (hydrochloride) | 29110-48-3 | 99.98% | 282.55 | 25 MG
Supplier: Medchemexpress LLC 25MGHY17416R
Guanfacine hydrochloride is an orally active and blood-brain barrier permeable noradrenergic α2A agonist, highly selective for the α2A receptor subtype. It has effects in producing hypotension and sedation, and can be used for research on various prefrontal cortex (PFC) cognitive disorders, including Tourette's syndrome and attention deficit hyperactivity disorder (ADHD).
- Orally active and blood-brain barrier permeable noradrenergic α2A agonist.
- High selectivity for the α2A receptor subtype.
- Increases delay-related neuronal firing needed for working memory on dIPFC neurons.
- Improves PFC cognitive function by inhibiting CAMP production, closing HCN channels, and strengthening PFC networks.
- Enhances PFC working memory function and improves impulse control in aged monkeys.
- Improves cognitive performance when infused directly into the rat or monkey PFC.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?