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Medchemexpress LLC Guanidine hydrochloride | 50-01-1 | 98.0% | 50 G
Supplier: Medchemexpress LLC HYB0178A50G
Guanidine hydrochloride is a strong chaotrope and a strong denaturant of proteins, intended for research use only.
- Refolds acid-unfolded apomyoglobin and cytochrome c at low concentrations.
- Causes co-operative unfolding of the molten globule state at concentrations greater than 1 M.
- Does not affect ordered structure remaining due to disulfide bonds.
- Causes efficient loss of the normally stable [PSI+] element from yeast cells at millimolar concentrations.
- Reduces Hsp104-mediated basal and acquired thermotolerance.
- Reduces Hsp104's ability to restore activity of thermally denatured luciferase.
- Significantly reduced death rate of infant mice infected with coxsackievirus A16 in vivo.
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