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Guanidine Hydrochloride, Ultra Pure grade, MP Biomedicals

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Quantity:
100g
1kg
50-01-1
CH6ClN3
95.53
MFCD00013026
PJJJBBJSCAKJQF-UHFFFAOYSA-N
guanidine hydrochloride,guanidinium chloride,guanidine, monohydrochloride,aminoformamidine hydrochloride,aminomethanamidine hydrochloride,guanidine monohydrochloride,guanidine hcl,guanidine chloride,iminourea hydrochloride,carbamidine hydrochloride
5742
CHEBI:32735
guanidine;hydrochloride
C(=N)(N)N.Cl
50-01-1
CH6ClN3
95.53
MFCD00013026
PJJJBBJSCAKJQF-UHFFFAOYSA-N
guanidine hydrochloride,guanidinium chloride,guanidine, monohydrochloride,aminoformamidine hydrochloride,aminomethanamidine hydrochloride,guanidine monohydrochloride,guanidine hcl,guanidine chloride,iminourea hydrochloride,carbamidine hydrochloride
5742
CHEBI:32735
guanidine;hydrochloride
C(=N)(N)N.Cl

  • Guanidine Hydrochloride is a strong chaotropic agent useful for the denaturation and subsequent refolding of proteins
  • This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies
  • This can be used as the first step in refolding proteins or enzymes into their active form
  • Urea and dithiothreitol (DTT) may also be necessary
  • Guanidine HCl is used in the isolation of RNA to dissociate the nucleoprotein into its nucleic acid and protein moieties
  • It is an inhibitor of RNase
  • Highly concentrated (6 - 8 M) Guanidine HCl solutions are used to denature native globular proteins
  • It apparently disrupts hydrogen bonds which hold the protein in its unique structure; however, there also is evidence suggesting that guanidine hydrocholoride may disrupt hydrophobic interactions by promoting the solubility of hydrophobic residues in aqueous solutions

Quantity 100g
Color White
Melting Point 180°C to 190°C
Linear Formula CH5N3·HCl
Solubility Information Soluble in water (6 M - clear, colorless solution).
Formula Weight 95.53
Physical Form Crystalline Powder
Percent Purity ≥99%
Grade Ultra Pure
Chemical Name or Material GUANIDINE HYDROCHLORIDE

Recommended Storage : Store at Room Temperature (15-30°C). Store Desiccated.