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AdipoGen Guanosine 5-triphosphate Na
Supplier: AdipoGen CDXG0069M250
Chemical. CAS 36051-31-7. Formula C10H16N5O14P3 . xNa. Molecular Weight 523.18 free acid basis. Guanosine 5-triphosphate GTP trisodium salt activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation and activation of several intracellular kinase cascades. Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle GTP functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. It also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA. GTP is involved in the initiation of peptide synthesis during the binding of formylmethionyl-tRNA F-met-tRNA to the ribosome. It is also involved in polypeptide chain elongation.
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