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Cayman Chemical Gunylate Cyclase 1 subunIt 1ea

Supplier: Cayman Chemical 1608971 EA

A potent agonist of GPR35 orphan receptors (EC50 79 nM in aBarrestin recruitment assay) induces GPR35 translocation from the plasma membrane to the cytoplasm (EC50 22 nM) increases ERK1/2 phosphorylation in a concentration-dependent manner in U20S cells expressing human GPR35a has antinociceptive effects in a mouse abdominal constriction model of visceral pain perception (ED50 40.5 mg/kg)
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