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Medchemexpress LLC GW2580-d6 | 2733770-48-2 | 98.4% | 372.45 | 10 MG
Supplier: Medchemexpress LLC HY10917S10MG
GW2580-d6 is the deuterium labeled GW2580, an orally bioavailable and selective inhibitor of c-Fms kinase. It completely inhibits human cFMS kinase in vitro at 0.06 μM by competitively inhibiting ATP binding and suppressing colony-stimulating-factor-1 signaling. It is suitable for use as a tracer and an internal standard for quantitative analysis in various analytical methods.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes incorporated into drug molecules largely serve as tracers for quantitation during drug development
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs
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