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Medchemexpress LLC GW6471 | 880635-03-0 | C35H36F3N3O4 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY15372100MG

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GW6471 is a potent PPARα antagonist that inhibits GW409544-induced activation of PPARα with an IC50 of 0.24 μM. It significantly inhibits cell viability in Caki-1 and 786-O renal cell carcinoma cell lines in vitro. In vivo studies demonstrate its antitumor activity, showing decreased tumor growth and c-Myc levels in xenograft mouse models without observed toxicity.

  • Potent PPARα antagonist
  • Inhibits cell viability in renal cell carcinoma cell lines
  • Demonstrates antitumor activity in vivo
  • No toxicity observed at effective doses in animal studies
  • Cited in numerous publications, including Nat Metab, Cell Metab, and Immunity

Catalog No. 50-003-76042


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